Healthcare operations leaders today must drive operational efficiency and cost management to achieve necessary clinical outcomes. New models of care coordination and accountability require new operational strategies that integrate hospitals’ business functions and medical mission. As reimbursements shift to pay-for-performance, hospitals and healthcare systems increasingly must work with a broad range of partners toward population health management, extending beyond the walls of their institutions. Physician alignment with this changing dynamic is essential, but getting incentives right can be difficult. HealthLeaders Media convened a panel of healthcare COOs to discuss how they and their systems can meet these demands and stay viable.